Pro-Banthine???

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grimaldi

Well-known member
Did anyone here use this antohilnergic Pro-Banthine for reducing sweating? I have been on it for some 3 months now and I don't find it reliable. Sometimes it works close to wonders but sometimes it doesn't do a shit, and usually its time of efficiency it just too short (below 6 hours for most of the days)

Anyone else here who can share their experience on this drug, and why it might be less efficient than Robinul (which I haven't yet used)

Thanks!
 
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grimaldi

Well-known member
Edit: the side effects are quite terrible. After taking 4 pills (60 mg total) the throat is like a dust road and once i couldn't even speak in class because of this so I had to ask the (unknown) guy beside me if he could pour half his bottle of water into mine. Urinating or taking a dump becomes irregular as well.

I wouldn't mind this at all if it at the same timed stop my sweating, but as you can see above IT DOESN'T.
 
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dougy

Well-known member
Hmm, I find taking 15mg of Pro-banthine works well for all areas, pretty much completely dry though it only lasts about 3 hours at most so that's a shame. Perhaps 30mg will last longer?
 
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grimaldi

Well-known member
i took 30 mg today and it worked somewhat but i still sweated on chest and back when i shouldn't (in a normal conversation in an air conditioned canteen) however, the sweat was not as bad as going through my shirt.

mate if you take 30 mg it will give you a much better effect. 15 mg is kind of nothing. as you self stated, such a small dose will leave the body very fast.

it also depends on the temperature, how stressful your day will be etc. BUT THE MOST IMPORTANT and listen carefully, is food intake. You should take this stuff on empty stomach, and then do not eat in the coming two hours. Skip you breakfast, that is. Try to take it on empty stomach and you will notice the difference i promise you....

thanks
 
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grimaldi

Well-known member
by the way i will go back to 45 or 60 tomorrow again. 60 kept me dry yesterday from 11 am to 7 pm then i started to sweat again, but less than normally even then.
 
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dougy

Well-known member
Thanks mate, it's good to talk to someone who is actually taking this medication as Ditropan and Robinul (Avert) are the most talked about for HH. I think you're right mate about the 30mg, I took 30mg at about 3.00pm the other day as I was going out and I'm pretty sure I was pretty much completely dry until midnight. I was out the whole time as well, so this could be a step in the right direction.

Good advice about the food intake. I'm pretty sure I took it right before I ate or right after I ate and it seemed to work so perhaps I'm different in that sense? But good to know if it doesn't work on certain days, I can try taking it on an empty stomach.

I got Ditropan the other day as it seems this is one of the medications that works well for HH, but for some reason it didn't really do much for me. I tried 10mg, perhaps that's a small dose?

Hmm, maybe Pro-banthine is my med, just got to keep experimenting to see what works best for me.
 
teandtoast

teandtoast

Well-known member
I take it and it works pretty well for me as long as its not boiling hot and sunny outside (or I manage to keep out of the sun)
also you have to make sure you take on a empty stomach
I usually take 30mg when I wake up an hour before i go to work then 2 hours later I take another 15mg and 2 hours later another 15mg ...that usually lasts me then from 9-5pm at work (I do office work so nothing to hard) ...if I was doing something more physical I would probably need more
I dont eat till usually 2pm either ...is a bit annoying but at least then the tablets work pretty well and you get used to it
If Im going out for the evening or for the night I wont eat at all after having lunch at 2pm until Ive finished for the night ...and I can end up taking quite alot more tablets if I go out
usually works quite well
 
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grimaldi

Well-known member
jesus mate that's a lot of pro-banthine you are taking there. but why not, anyway. how much do you come up to during a stressful and long day? i had days when taking 105 mg, but i reckon the last dose doesn't do much anyway since i have food in my body when i take it.

but since you refrain from eating it might be different for you. did you lose weight? do you have any hints for keeping up the energy without eating, like chocolate, fruits etc? as for me, i eat a bog portion of pasta before i go to bed, so i can wait longer before having my first meal the next day....

also, did you reckon you build up any tolerance against pro-banthine? i definitely did, but it seem to "stop" at 60 mg, which have turned out to be the perfect morning dose for me. might slash it to 45 during winter. and do you have problems with urinating and/or taking a dump?

and dougy: there is definitely a difference when taking it on empty stomach or not. maybe you didn't realise it yet because of various factors (good days, bad days etc.). but to maximize the effect of the drug, DO NOT EAT two hours before or after taking it. keep yourself going with a soda or some candy.

thanks
 
teandtoast

teandtoast

Well-known member
well sometimes if Ive got loads going on during a day or Im going out all night I can end up taking a stupid amount of them like 1/2 - 3/4 packet of 15mg so like 20x15mg ...which is like 300mg ...probably theyre not even having much more effect after so much but where Im stressed and anxious I just keep taking them ...also when Im drunk I sometimes just take loads like that..
the other thing also is if I have eaten some food takes longer for the tablets to work so if u take more tablets say like 1 every half hour or something they start working quicker (as long as youve given it bit of time after the food)

I didnt lose weight...Ive always been quite thin really so made no difference to me
re keeping up the energy if you mean while on the tablets I dont think eating choclate or fruit etc would be good idea as that would be same as food and make the tablets stop working
drinks are always good though like tea or coffee ...
I find though you get used to it ...what Ive been doing recently is taking tablets at 7 / 9 / 11 ...then having cripsps at 12 and lunch at 1 ...usually the tablets are really kicked in by then and will last till 5

I didnt build up a tolerance strangely Ive been on them for like a year and half now and still seem to be doing their job well ...cant wait for winter again either will work even better again then

yeh Ive had problems taking a pee before like if the tablets are working super well thats when I find that happens and I get a dry mouth then at sametime...not to much of a prob though

I cant remember what tablets I used to take but it was robinul or one of the other talets but at the time I didnt know abbout the taking on empty stomach stuff n they never worked for me ...Im wondering now what one of the other tablets would be like in comparison to probanthine n if worked even better maybe if taken properly
tempted to try
u tried any the others grimaldi ?
 
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dougy

Well-known member
Thanks for the advice grimaldi. I was researching on the net and it seems that Pro-Banthine is most effective taking 30mins-1hr before eating or sometimes up to 2hrs. I took 30mg today at 12.30pm (when I woke up) and didn't eat until about 2.00pm. I got quite a dry mouth and actually had troubling eating, just had to drink a lot of water.

I did notice I was dry in all areas, was out from 2.00pm - 6.00pm. Remained dry everywhere except my underarms and my ass. I did notice some pretty extreme fatigue as I guess I'm not really use to this dose yet and I felt like my fingers were swelling. Haha, it was kind of like I was on a trip. A bit embarrassing when I was buying something at a shop and I could hardly talk due to the fatigue and dry mouth, haha oh well.

I'll keep trying 30mg first thing in the morning, I know my body will get used to the dry mouth and fatigue. Interesting about my underarms though, they must be very over-active as I've been trying Driclor and it can only stop the sweating up to a certain point. Waiting on my order of Odaban.

Hmm, do you reckon I should give 45mg a go or stick to 30mg for a week or so? What about trying Ditropan?
 
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grimaldi

Well-known member
teandtoast: jesus that's a lot. do you find any other side effects when taking those amounts? as for the eating, i don't think a banana or a piece of chocolate would completely destroy the effect of pro-banthine; it should probably been seen as some kind of grayscale/ladder, where the food "destroys" less if eating less, and more if eating more. but probably the best solution would be to eat dextrosol or some candy. i wouldn't go for coffee though because that's something that really do increase your sweating. i've been quiting coffee totally by now.

as for me, when i got the med, 15 mg worked quite well for me (only for a short time though - like 3 hours). now, three months later, 15 mg does nothing at all. but the does of 60 mg seems to have the same effect (fingers crossed) even after a month. and unfortunately i have not been able to get my hands on robinul. i was close in china but then i had to change hospital due to moving.

and by the way just want to add that my pro-banthine is produced in china, and comes in cans of 100 pills, 15 mg each. the guidelines/instructions are all in chinese, the only thing indicating it is pro-banthine is a small word saying "pro-banthine" on the can and my doctor's assurance. for sure it is pro-banthine, but i don't now if it might have slight differences from the one you get in...another country...

dougy: everyone i can help to fight this plague is another victory for me, so no need to thank. we all have our weak spots it seems; i will never be totally dry on my back and around my chest muscles however much pro-banthine i decide to take. but hands and face will stay dry though.

i really know the feeling of being so dry in the mouth that you can't speak; it happened to me in class just recently and i had to ask another classmate to pull half his bottle of water into mine, so i could keep talking during class. another thing that will give you tremendous relief is sugar free gum. try it tomorrow.

since the 30 mg dose gave you such good result, i would advice you to stay on it instead of increasing. not for the sake of danger, but for the sake of you body might will develop "immunity" to the drug faster if you higher the dose immediately. instead you should take 30 mg when you wake up, and another 30 mg again when you feel the first dose starts to lose effect. try to match it with your food intake, so you take it in between to meals.


and about the fatigue i don't know. i have been feeling very tired recently but that can also be due to other reasons (and other meds). logically, the way pro-banthine affect your body should NOT increase tiredness. but blurry vision and dry eyes and dry mouth might make you feel tired. what do you reckon, teandtoast?

and one last question: where do you guys live? i'm in hong kong and locals say it's the hottest summer for over 20 years. it constantly over 30 degrees celsius and doesn't cools during the night even. worse still, there is a humidity over 80 % every day, and often up to 95 %. it's totally ridiculous how soaked i am when walking home 15 min from school (i take the bus TO school, even though it doesn't save me any time)

good luck and keep fight this!
 
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dougy

Well-known member
I know I'm thanking you again grimaldi but it's just good to see someone else having some similar experiences. I will keep trying 30mg in the morning then when necessary. Is Pro-Banthine still working for you?

Oh geez, I'm in Australia but we have just come out of winter so atm the maximum temperature is 17-24C so I haven't really been on Pro-Banthine that much. Hard to test it out atm but I'm just preparing for the summer as it's brutal over here. Not so much for humidity but the temperatures are ridiculous.

Last summer we had 3 consecutive days over 43C (43.4C, 44.3, 45.1) and we broke the hottest day on record of 46.4C. That's 115.5F. Some places hit 48-49C, so you can imagine what it's like for a HH suffer, thankfully on those days it's not like you can do much anyway and everyone should be sweating anyway, just not excessively!

Oh well, at least this time I've got some kind of plan of action, hopefully I can make it through the summer.
 
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grimaldi

Well-known member
It's not working as good as I wish to. Some days I don't take it at all because I feel like it's "no idea". But it does offer relief, especially for nervous sweating I reckon in my case. Yesterday I had dinner with my gf's mother which is Cantonese so I can't communicate with her in any language. I use to think that's embarrasing; she cook me a hell of a good meal and I CAN'T SAY A WORD even to thank her.

One time she actually turned on a fan and directed at me because my forehead started to drip. Yesterday before going there, I had 45 mg Pro-Banthine and didn't sweat. Great feeling, and the pills also give me confidence that probably take the thoughts out of the head somewhat.

However, when going home, I sweated as **** during the 10 min walk from the subway to my home. It seems as Pro-Banthine for me become worthless after I eat?! However, I will use Pro-Banthine for social occasions, since it do some good although it doesn't feel completely safe every time.

Oh jesus funny about the temperatures. I am Swedish, really never experienced temperatures over 25 degrees. After six months in Asia, I haven't been in lower than 28-30 since arrival here in March. We had 42,3 in Beijing during July, but here in Hong Kong the humidity is even worse.

At least in Beijing, there are cool days and there are cruelly warm days. But here in Hong Kong, it hoovers around 30 degrees and 75 per cent humidity EVERY DAY. So when you waker up you'll know it's just another sweaty day.......

How's it going for you mate?
 
teandtoast

teandtoast

Well-known member
grimaldi said:
teandtoast: jesus that's a lot. do you find any other side effects when taking those amounts? as for the eating, i don't think a banana or a piece of chocolate would completely destroy the effect of pro-banthine; it should probably been seen as some kind of grayscale/ladder, where the food "destroys" less if eating less, and more if eating more. but probably the best solution would be to eat dextrosol or some candy. i wouldn't go for coffee though because that's something that really do increase your sweating. i've been quiting coffee totally by now.

as for me, when i got the med, 15 mg worked quite well for me (only for a short time though - like 3 hours). now, three months later, 15 mg does nothing at all. but the does of 60 mg seems to have the same effect (fingers crossed) even after a month. and unfortunately i have not been able to get my hands on robinul. i was close in china but then i had to change hospital due to moving.

and by the way just want to add that my pro-banthine is produced in china, and comes in cans of 100 pills, 15 mg each. the guidelines/instructions are all in chinese, the only thing indicating it is pro-banthine is a small word saying "pro-banthine" on the can and my doctor's assurance. for sure it is pro-banthine, but i don't now if it might have slight differences from the one you get in...another country...

dougy: everyone i can help to fight this plague is another victory for me, so no need to thank. we all have our weak spots it seems; i will never be totally dry on my back and around my chest muscles however much pro-banthine i decide to take. but hands and face will stay dry though.

i really know the feeling of being so dry in the mouth that you can't speak; it happened to me in class just recently and i had to ask another classmate to pull half his bottle of water into mine, so i could keep talking during class. another thing that will give you tremendous relief is sugar free gum. try it tomorrow.

since the 30 mg dose gave you such good result, i would advice you to stay on it instead of increasing. not for the sake of danger, but for the sake of you body might will develop "immunity" to the drug faster if you higher the dose immediately. instead you should take 30 mg when you wake up, and another 30 mg again when you feel the first dose starts to lose effect. try to match it with your food intake, so you take it in between to meals.


and about the fatigue i don't know. i have been feeling very tired recently but that can also be due to other reasons (and other meds). logically, the way pro-banthine affect your body should NOT increase tiredness. but blurry vision and dry eyes and dry mouth might make you feel tired. what do you reckon, teandtoast?

and one last question: where do you guys live? i'm in hong kong and locals say it's the hottest summer for over 20 years. it constantly over 30 degrees celsius and doesn't cools during the night even. worse still, there is a humidity over 80 % every day, and often up to 95 %. it's totally ridiculous how soaked i am when walking home 15 min from school (i take the bus TO school, even though it doesn't save me any time)

good luck and keep fight this!
Click to expand...

side effects after taking that much is I cant eat the next day as my mouth/throat are weird and makes eating/swallowing food like hard work and not nice experience

i wouldnt have thought any difference between the pills u get and ones get here (in the uk)

Ive not had any problems with tiredness caused by pro banthine ...I usually feel tired most of the time anyway from depression / anxiety etc anyway lol

I wouldnt be able to cope where u live and that heat ...be too much for me
when gets a bit hot here (england) the pills dont work for me so in ur kind of heat they would be of no good to me at all :/
 
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dougy

Well-known member
Hi grimaldi and teandtoast,

I'm just wondering how bad your hyperhidrosis is? Like generalised or are there specific parts? Damp/Wet/Dripping etc? What sets it off?

I know HH is individual but maybe I can gather some kind of picture from you two and compare it with me and the use of Pro-Banthine.

Atm I haven't been using Pro-Banthine as it's not warm enough so I don't want to use it when unnecessary. Just been using Driclor and Odaban for the hot spots and wearing dark/darker clothes.

Also going to talk to my GP about different medication such Robinul, Ditropan, Pro-Banthine and Clonidine.

I'm kind of interested in Clonidine due to it's long half-life of 12-33 hours. Though probably won't be effective. Pro-Banthine is pretty poor in that regard, with a half-life of 1.6 hours (this is why Pro-Banthine is not lasting long for us) and Robinul 1.7 hours (average 0.6-4.6 hours). Ditropan has quite a long half-life of 12.4-13.2 hours which suggests to me why some people can take only 5mg of Ditropan a night before going to sleep at it lasting all day the next day.

The only thing that worries me about Clonidine and Ditropan is that they cross the blood-brain barrier, so will talk to the GP to see how bad that really is and potential complications.

How's it going for you guys btw? Sorry about all the info and questions, just like to have the most information/research as possible and perhaps help you guys too.
 
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grimaldi

Well-known member
Hi, I'll paste my post from another thread named "how bad is your generalized HH":

----

(...)

I can give a couple of examples: I use to walk home from my university here in Hong Kong, it's a 12-15 min walk, downstairs. For about a month ago, the weather on the evenings was about 32 degrees and some 75 per cent humidity. After the walk I had large sweat stains and front and back, and the sweat also showed through my jeans if I had jeans. My socks changed color because of the sweat.

Now, it's around 30 degrees and just over 60 per cent humidity. I walk the same way and front and back are still stained, but I don't get through the jeans if it's not 70 per cent humid or more. Humidity is worse than temperatures. In both cases I had friends walking the same way; none even sweated through a single clothing or even at forehead.

Also by only standing in the sun I will begin to drip, but then "only" between my breast muscles and the lower/mid-lower back. A couple fo weeks ago, 9 a.m., standing in the morning sun chatting with classmates. Had to go in to the lab again after 3-5 minutes, because my shirt started to change color in the front, which was directed at the sun.

My magic border seems to go at 26 degrees, 70 per cent humidity. If it's over any of that, I sweat by just sitting down.

Needless to say, during workout, I look like a complete freak. Even though air cindition inside, if I play squash for an hour, there is a darker color from sweat on about 90 per cent of my t-shirt. I can take it of and wrap the sweat out. Same result if i jog or doing skip rope outside for 20 min, if it's 25 degrees.
 
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dougy

Well-known member
Thanks for the quick reply. Your HH does seem quite severe. Humidity would be worse then actual temperature as it takes longer for the sweat to evaporate.

I think generally my HH is mild with severe for the underarms and mild-high for the forehead/back/lower regions in summer. But it does not make it any easier, I hate the sticky feeling and just wanting to go home and freshen-up. Makes you feel like a nervous wreck ugh.

Percentage wise, how much does Pro-Banthine reduce your sweating as well as how long do you find the dose effective for? Also, have you looked at any of the other medication I mentioned early? I know you can't obtain Robinul atm but have you tried/looked at Ditropan or Clonidine?

Would be good to hear your thoughts and reasons. Thanks mate.
 
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grimaldi

Well-known member
Yeah my HH is ****ed up and it's actually disabling in the sense that I could never spend my life in Hong Kong but I have to move to a more northern location, even would I been offered a good work here. It's just no way I will spend more time than necessary feeling clamming and disgusting every day.

I have basically stopped taking Pro-Banthine. I have started with a new remedy consisting of L-Methonine, Calcium, Magnesium, Zinc, Vitamin C. You can read about it under the thread called "Histadelia can be the answer" on this forum. I am also drinking sage tea, but I started with all this yesterday so there is no way of telling how it works.

I am looking for a long-term solution and Pro-Banthine is not. I still take it before I am going out to have a drink, have a dinner etc. but as for the long days spent in a/c classrooms I just don't care anymore. This morning I walked to school and even though only 23 degrees had stains on me, which was uncomfortable but I'll dry up fast in the a/c classroom.

Results vary A LOT from time to time, and the insecurity of Pro-Banthine is also one reason why I stopped taking it.

Moreover, when sweating decrease my blushing and palpitations tend to increase?! Therefore my problems ain't being totally solved by stopping sweating anyway. I just hate this so much, god let there be an end....
 
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dougy

Well-known member
Yeah far out, it's about time that the medical world took HH more seriously. It can be very disabling and can easily lead to anxiety and depression. You would think HH would be the cause for a lot of the anxiety and depression in HH suffers, so fix the source of the cause?

Yesterday it was 28C, was sitting in the sun with some friends and my forehead and hair was getting quite wet. Looked around and no one even had the slightest bit of sweat.

Yeah, Pro-Banthine can be unreliable. It dried me up yesterday including underarms but 2 hours later I was sweating at the underarms again. Should last longer than that??

I'm so over this, it's a ridiculous condition. Let me know how you go with this new remedy.
 
Rexus

Rexus

Well-known member
grimaldi said:
Edit: the side effects are quite terrible. After taking 4 pills (60 mg total) the throat is like a dust road and once i couldn't even speak in class because of this so I had to ask the (unknown) guy beside me if he could pour half his bottle of water into mine. Urinating or taking a dump becomes irregular as well.

I wouldn't mind this at all if it at the same timed stop my sweating, but as you can see above IT DOESN'T.
Click to expand...

This is exactly why Ditropan made me feel like crap + the fact that you feel stupid/hazy all the while when on it. And to become dry, I remember having to urinate a couple of times to dry yourself up. And then you keep on urinating all throughout the day. It's terrible.
 
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